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Professor Dewey is a professor in MIT's Mechanical Engineering Department and holds joint appointments in the Division of Bioengineering & Environment Health and the Division of Health Science and Technology. He is also Co-Director of the International Consortium for Medical Imaging Technology (ICMIT) whose goal is the development and promotion of advanced technology for medical imaging. Professor Dewey's research interests include fluids mechanics, cell dynamics and modeling, biomedical imaging, medical informatics, and instrumentation.
 

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Research Highlights

Actin Dynamics in Vascular Endothelium
DICOM medical database
Physiome project
Educational project

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Graduate Students

Yuan Cheng
William Chuang
Ngon Dao
Christopher Hartemink
Eric Osborn
Orion Richardson
Shixin (Jason) Zhang

Recent Alumni

Patrick McCormick
Matthieu Ferrant (visiting student from UCL, Belgium)
Yoshihiro Yasumuro (visiting student from NAIST, Japan)

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Selected Publications

1. Satcher J, R. L., Bussolari SR, M. A. Gimbrone J, C. F. Dewey J. The Distribution of Fluid Forces on Model Arterial Endothelium Model Arterial Endothelium Using Computational Fluid Dynamics. J. Biomechanical Engineering 1992;114:309-316.

2. Tardy Y, McGrath JL, Hartwig JH, C. F. Dewey J. Interpreting Photoactivated Fluorescence Microscopy Measurements of Steady-State Actin Dynamics. Biophys. J. 1995;69:1674-1682.

3. Dewey J, C. F., Thomas JD, Kunt M, Hunter IW. Prospects for Telediagnosis Using Ultrasound. Telemedicine Journal 1996;2:87-100.

4. Virtual Files: The Key to Managing Medical Images (Abstract). Ann. Proc. Fall Meeting of Biomedical Engineering Society; 1996.

5. Tardy Y, Resnick N, Nagel T, M. A. Gimbrone J, C. F. Dewey J. Shear Stress Gradients Remodel Endothelial Monolayers in Vitro Via a Cell Proliferation-Migration-Loss Cycle. Arterios., Thromb., & Vasc., Biol. 1997;17:3102-3106.

6. Satcher, R.L., Dewey, C.F. Jr., and Hartwig, J.H. Mechanical Remodeling of the Endothelial Surface and Actin Cytoskeleton Induced by Fluid Flow. Microcirculation 1997; 4:439-453.

7. Extending Dicom Databases to New Imaging Modalities (Abstract). Proc. World Congress on Medical Physics and Biomedical Eng.; 1997 Sept. 14-19, 1997; Nice, France.

8. An Object-Relational Architecture for a Dicom Medical Image Archive (Abstract). Proc. World Congress on Medical Physics and Biomedical Eng.; 1997 Sept. 14-19, 1997; Nice, France.

9. Dao N, Dewey CF. Databasing Strategy for the Human Physiome, (Abstract). Ann Biomed. Eng'g 1998;26 (Suppl. 1), S-13.

10. Dao N, Dewey CF, Jr. Design and Prototype of a Database for Medical Images, (Abstract). Ann. Biomed. Eng'g 1998;26 (Suppl. 1):S-13.

11. McGrath JL, Tardy Y, C. F. Dewey J, Meister JJ, Hartwig JH. Simultaneous Measurements of Actin Filament Turnover, Filament Fraction, and Monomer Diffusion in Endothelial Cells. Biophys. J. 1998;75:2070-2078.

12. Dewey, C.F. Jr., Kitney, R.I. Creating DICOM-Enabled Clinical Systems with Robust Image-Querying Capabilities. Proc. Towards An Electronic Patient Record '98; C. P. Waegemann, editor. 1998 May 9-15, 1998; San Antonio, TX. Medical Records Institute.

13. McGrath JL, Hartwig J, Tardy Y, C. F. Dewey J. Measuring Actin Dynamics in Endothelial Cells. Microscopy Research and Technique 1998;43:385-394.

14. Nagel, T., Resnick, R., Dewey, C.F. Jr., and Gimbrone, M.A. Jr. Vascular Endothelial Cells Respond to Spatial Gradients in Fluid Shear Stress by Enhanced Activation of Transcription Factors, Arteriosclerosis, Thrombosis, and Vasc. Biol. (accepted for publication, 1999).

15. Dao N, Dewey, CF Jr. Preliminary Database Strategy for the Microcirculation Physiome Project. Annals of Biomedical Engineering 1999;submitted for publication.

16. Cheng Y, Hartemink C, Hartwig JH, Dewey CF, Jr. Three Dimensional Reconstruction of the Cell Cytoskeleton from Stereo Images. J. Biomechanics;(accepted for publication, 2000).